From Neurophysiological Signals to Clinical Decisions

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About

We develop and translate rigorous machine learning and wearable-based technologies to improve diagnosis, monitoring, and treatment of epilepsy and neurological disorders. Our work bridges neuroscience, signal processing, and data science, with a strong emphasis on real-world clinical relevance.

  • FOUNDATIONS

    Understanding Epilepsy Through Signals

    Epilepsy is characterized by complex and dynamic brain activity that unfolds across multiple spatial and temporal scales. Our work is rooted in neurophysiology and signal processing, with a focus on extracting meaningful information from scalp and intracranial EEG recordings to better understand seizure mechanisms and brain network dynamics.

  • FROM SIGNALS TO MODELS

    AI for Detection, Prediction, and Monitoring

    We develop machine learning models that translate multimodal signals, including EEG, wearable sensor data, and medical imaging, into interpretable and clinically meaningful outputs. Emphasis is placed on robustness, generalizability, and validation under real-world conditions rather than performance on curated datasets alone.

  • COMPLEMENTING CLINICAL EXPERTISE

    Toward Data-Informed Care

    Modern epilepsy care generates rich neurophysiological and physiological data across hospital and ambulatory settings. Our research explores how advanced signal processing and artificial intelligence can complement clinical expertise by organizing, summarizing, and interpreting these data in ways that support diagnosis, monitoring, and longitudinal care.

  • REAL-WORLD IMPACT

    Clinical and Ambulatory Deployment

    A central focus of the lab is the development and validation of technologies that extend epilepsy care beyond the clinic. By integrating clinical constraints into model design, our goal is to support objective monitoring, personalized therapeutic strategies, and continuity of care in both hospital and home environments.

Our Amazing Team

Our staff and fantastic students all come from varied backgrounds, from biomedical engineering, neuroscience and astrophysics!

Group picture in 2025

Elie Bou Assi, PhD

Professor

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Manon Robert

MEP Technologist

"The Lab's Mom"

François Hardy, Ph.D.

Data Scientist

"Coding Guru"

Amirhossein Jahani

Postdoctoral Researcher

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Daniel Alejandro Galindo Lazo

Ph.D. Candidate

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Darion Toutant

Ph.D. Candidate

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Isabel Sarzo Wabi

Ph.D. Candidate

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Marilie Chalifoux

Student

"Curious mind"

Ralph Saber

Postdoctoral Researcher

"Medical AI Guy"

Sarra Chebaane

M.Sc. Student

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Alumni

Previous members of the lab

Brian Aboujaoudé

Research Intern

Camille Bégin

Research Intern

Chloé Bernardoni

Neuro-engineering M.Sc. Student

Valérie Costa

Robotics M.Sc. Student

Tian-Yue Ding

Research Intern

Oumayma Gharbi

Neurosciences M.Sc. Student

Raphaëlle Hartwig

Biomedical Endineering M.Sc. Student

Mezen Jemel

Research Intern

Naomi Laflamme

Research Intern

Yassine Lamrani

Research Intern

Émile Lemoine, MD, Ph.D.

Biomedical Engineering Ph.D. Student

Julie Le Tallec

M.Sc. Student

Dumisani Lickson Namakhwa

Research Intern

Antoine Magron

Data Science M.Sc. Student

Emmanuelle Nguyen

Research Intern

Carole Ruppli

Micro-engineering M.Sc. Student

Jérôme St-Jean

Neurosciences M.Sc. Student

Jean-Daniel Tessier

Research Intern

AnQi Xu

Research Intern

Expertise

Our expertise lies at the intersection of neuroscience, signal processing, artificial intelligence, and wearable technologies, with a strong focus on clinically meaningful applications. We develop computational methods that are informed by neurophysiology, validated on real-world data, and designed to support epilepsy care across clinical and ambulatory settings.

Artificial Intelligence

Neurophysiology

Wearable Technologies for Epilepsy

Publications

Here is a list of published papers by our team.

Jahani et al. (2026)

Epilepsia

Lemoine, Toffa et al. (2025)

Brain Communications

St-Jean et al. (2025)

Epilepsia Open

Jahani et al. (2025)

Frontiers in Network Physiology

Lemoine, Jemel et al. (2025)

Epilepsia

Ding et al. 2024

Epilepsia Open

Gharbi et al. (2024)

Epilepsia

CONTACT US

Feel free to contact Elie Bou Assi
if you have any questions or comments.